Supports Heart Health*:
Herbal Gos formula contains 4 ingredients that supports heart health: Evodia, Solomons Seal, Green Tea, and Cinnamon Bark.
Evodia helps to decrease blood pressure (anti-hypertensive). Decreases in diastolic blood pressure were more dramatic than systolic pressure, implying a vasodilatory effect. (4)
Evodia assists in normalizing rhythmicity of the heartbeat (anti-arrhythmia).(5)
A recent study also demonstrated that when Evodia was fed to mice on a high-fat diet in the form of an alcohol extract (.02pct.) for 21 days, total body weight, perivisceral (abdominal) fat, epididymal (testicular) fat, and total cholesterol, lipids, (fats) and triglycerides in the liver were significantly reduced as compared to the control group. (1)
Evodia supports heart beat contractions and the hearts pumping capacity. (6)
Evodia aids in the prevention of cardiac anaphylactic injury associated with stimulation of calcitonin gene-related peptide (CGRP) release, which combats cardiac anaphylactic injury. (9)
Evodia helps to increase cerebral blood flow (cerebrovascular health). (3)
(1) Kobayashi Y, Nakano Y, Kizaki M, Hoshikuma K, Yokoo Y, Kamiya T. Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist. Planta Med. 2001 Oct; 67(7):628-33
(3) Pei-Hsuan Hung, Lie-Chwen Lin, Geui-Jane Wang, Chieh-Fu Chen, and Paulus S.Wang. Inhibitory Effect of Evodiamine on Aldosterone Release by Zona Glomerulosa Cells in Male Rats. Chinese J of Phys June 30; Vol 44: No 2, 2001.
(4) Chiou WF, Liao JF, Chen CF. Comparative study of the vasodilatory effects of three quinazoline alkaloids isolated from Evodia rutaecarpa. J Nat Prod. 1996 Apr; 59(4):374-8.
(5) Loh SH, Lee AR, Huang WH, Lin CI.Br J Pharmacol. Ionic mechanisms responsible for the antiarrhythmic action of dehydroevodiamine in guinea-pig isolated cardiomyocytes. 1992 Jul; 106(3):517-23.
(6) Kobayashi Y, Hoshikuma K, Nakano Y, Yokoo Y, Kamiya T.The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa, on the guinea-pig isolated right atria: possible involvement of vanilloid receptors. Planta Med. 2001 Apr; 67(3):244-8.
(9) Wu CL, Hung CR, Chang FY, Lin LC, Pau KY, Wang PS. Effects of evodiamine on gastrointestinal motility in male rats. Eur J Pharmacol. 2002 Dec 20; 457(2-3): p. 169-176.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.